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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e065a7ad731945c62a8d9b7feb7d161655ecf77b3c6c90c6a0f2ccb18f65ef' 
  AND token = 'Qe/XGEwKrN4ff03BdfPhPDyJXjZpZxV5nghCcHgW2Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}