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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce38a283c1bf1e41a434080172c5739681cf61752ab3a6237da53f0b5b1571f8' 
  AND token = 'zhM+OVOUQtuDsS8RmuIvJQD/WYy2akfGJnuxbs0b1u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}