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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b768d5c6e7bc4afe4384572486c48f90336d5f3ec32d6220da0addf3e64caee1' 
  AND token = 'MZIhf9WmOmt94EV6aJw/3B6nbGDcjLRFIm0uqMnFSls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}