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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7da9ce91f79b27025a9ffa129470f065cc4f69d12d129abe97a5f191a3d7c856' 
  AND token = 'Sw2DNXAW+MfdxBhRBe9l/x6b6nmbF1uvNi9hpjCGAA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}