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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f7eb4318ac37c863140d2ed9466f5bb0bd521b9def5edcc17ca521b2247a1e' 
  AND token = '7PDg+ahpzEzZOAse3I+bEXyI4dvBzxRtfNpnlgh4g0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}