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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5115fb6181827816e75bb6eda4a83ec381000e7f160b0bab4a678b4f16f3e5ea' 
  AND token = 'DQumUSI8EmEyv8F0ZkGxkGP93I0PEYy1UqU+obeGsVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}