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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a3287cf67512bba63f4cad8c49c2eea9901bf8acda2f2392d105b6e78c312e6' 
  AND token = 'LT0aAxPvdnTJbdEFG8qEIdvHb4myFUi/6r5ek9GRtpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}