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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf46d1aeedf708c9c7ff9199c053f2ccd44490123bcbe17c6b17bd99afd87d11' 
  AND token = 'Q2QrCbp/fRvgI8AkBMka2tjPn+XTBmDnXMpK0MHPibU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}