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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43781426f944d60387288a02f5e37c68cd88225b6127292b2f41214e6954059' 
  AND token = 'sKsUUHAeK0oSdd+o4C6q/m6cl8WGyGW7Znx1SV2Juj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}