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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26efc562954764e6dc885f965f65e6a46b6f424161101d9e7e8c009f4685f440' 
  AND token = 'CDKQpOqslOSu3g3XhAvCXy3m1d2L+/+p7U6mkzY7Ayk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}