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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fd6ccde212673f5c3da4095ea0e612aa5eab727cc6b17a4ee138acb00749734' 
  AND token = 'Zws17I4uqR8f5Bvara0cWyDfW9iMcbWAdqjoLXqyUaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}