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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3377b7195fb2f5dbe3d0eee5c1613f84d63bdfa05f1f3d1d25a915f7f13b9adf' 
  AND token = '+MW8KgHautqXXFcOUKIxyrM1OftRa1umnSYhw7xVrZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}