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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc5220c30034e29c30525153f317f3c9b16bd362867cfe46ca7a90adc9955b8f' 
  AND token = 'd+d0YtZmpd3/CivOlKTwIQTM0kkGqAMZ7bAqQInHYR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}