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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8439ba0e792f2932d6f312ed257ca1d37f7753b9c9ee792b336cbe2c229dfb2a' 
  AND token = 'OyY21E9Ez2afwP4o7N10mVdrKtEGd5mIf8OAfs3tP4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}