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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf841acf9a0512af8867d97da225e4951dc6a28f61a1c0556043f3a35382adb4' 
  AND token = 'V6cMVgLe9QKc01zxlDX2xMqtzO1Ge5iC2tFgMMJtkUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}