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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b64689d440a837228a052d83c2e35759e225ada37b2e6ae1f1241a4051bf584' 
  AND token = 'zs7D6eTC1BvhfwxQfQr8bUASFxVZnRsgeb2LkPMfVgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}