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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4529057478c72de61e9801f011e58d392e96a67658b1ed7dd751d53d3bf22a32' 
  AND token = 'I0FBH18kAGdzH1k9qQzPwYAS0EJ5kWfc03oLFk/ZIzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}