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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b77585e18f7d9a626f4f4a2d3ec29909d029469424c74f8a772b07c77f1d1b' 
  AND token = 'H7mKND1DhU50rxACBH5ldPrt2C2MYQaXAMiT4afA9PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}