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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a8c06c9e6cb464e6e70766b08718cb6637b7f29f3ba446f35243a504b57e4e' 
  AND token = 'aIIt47lPx94+4RvssknVHW9Y+DZJCNwocscqm0G4/iQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}