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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290cc57ab9749211be28ec4fdb43bdd0114a0fe8abb82b4c00d3ec72cebf6e16' 
  AND token = '9iL84UbuY9ciRCMY1nkv5NCOMXMsf7s2CtO5d91Do4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}