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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eea0c7fd9eb750e33308f802a474d0270cd030b8ca0f38a634ce4040e958115' 
  AND token = 'GHPeGFeDtr+HZmvfomRnS/7S9gH14OQhXBkAiuUVxqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}