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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8923e2eeb586d86d7270d865d4c4eb0d51672e473ad462d569e4d55041bd1f12' 
  AND token = 'pIJeQp+AdMLfiyL3dc0483t29VgCqu0LutcXQe3JsfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}