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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42836d1845e6a6e06171949c1832d54b9c4701a302d8119fb5c1eb9abd15357' 
  AND token = 'WRKJyoqWcJxNTCGgT8s8HuFkRgTcb1CV4C0ZoP1F8jU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}