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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1c370f1e6f48b58478d5d87cfc1ed5800cc5403506068501362222f651f96f5' 
  AND token = 'ip4fjTQIO80CexrprZ+u4GgW4SVZeoEGd0S2jg88HQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}