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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf6cd0aac8a4e4f28f98f9b349322430e1f2c222a4efe2773677b79e8587332' 
  AND token = '2EPFGcuUIxUJF3TWgr3RBGFs4AzZ/SO9BFJSRkh8qMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}