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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2fe87d68e105d0376582d413df0d94e5d658275a9ab01a71d97e0221e4fe72d' 
  AND token = 'EPaNDdhQv8HGKOCi/qdHEQ22p4msEdqOBMgSLc8yV+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}