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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa25e139591b067e4eecb2c540bd63051e86a048a8cbbcd30055c62ac6e9a65' 
  AND token = 'FX3m/BAgy86Q6we5Nssnp3XjrF9pxiExOyLSiW5WR2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}