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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0279de3cad706fec617192774113d17df3041b163c8a373aab2d36b750fda1' 
  AND token = 'pLNdDN4D6dBJpj3+y2YmzigUrk0pE68kCy2Bsq1N+lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}