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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d09cdc3dfd3adbb8d5cad67df6e958464bc4e820a165e2f25a0dd1abf633840' 
  AND token = '2b7m48yMSFkiZ1um+P0nLymiWbo1TeCB89e8VnjJCaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}