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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40bd95bf24dd130d98ee7b36c94ceceee2060476ba7ec48ca356fd3c38ec7010' 
  AND token = 'MsVcCVdHoWAFzqty1Ye/VvdJbLi+C5xlibMAee+22Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}