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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aa64be97b4ba41a0e06b220e5d4a249c9361337c09dc4b347b5388a909b8731' 
  AND token = 'kXX1D3kuCQYN1TYCXkAlEjTESMXaFc2JrHbdbbGuf6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}