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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '913ef78a80873461d834b6ba3c6b130c29eb8bfda0c74de48cf359514e823173' 
  AND token = 'NBirEHfhG8b11fqtr1HcJ+pjV4ONlSyhrYyAOWzBuSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}