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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '207167073713d7432b7265343d9cd8478fb2d13a4d58d092b76416acc56df4a3' 
  AND token = '5HSqn8VUY6jjdIVolN28gTeLYkdIHa6d6fIk63Ui4Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}