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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c56fcf4c81a7c681b25baeafb36b6100eac3757e79ae3523e5c3dd3dc77f5f52' 
  AND token = '4C6PnoIid8Izfd/jksb5MGz6+hYOZBtWtSRbH+usHwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}