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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748e8702bd93dfa874eef66242d918fb828adbbe9636cdbef097add1e2bf0423' 
  AND token = 'Bf2/05ZGhIt8hGvnSCibCNS8kLn8zeqTnfSzUP5hSq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}