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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503f5cbc9b825b40058dd514c24083fcee6c4299004476f54ed2df7a7b6b0546' 
  AND token = 'IwqexZheG3s8TjN7g8dF6CZ5SfiOCBHaleTxsXRgcOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}