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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c660314a1595d15714d22f52fe0514c7a32cece0824b42a4ef5d5e9c6c04a3c' 
  AND token = 'Ve5n08XnutNFoOBCjisWT/5Zc1i9haz8321SoYliWlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}