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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b15006e14f52e71a204279e55e7c7169f283147fdaa4b53d9f2035d65f38cd9d' 
  AND token = 'iZmya/S8LOhCwWp3vm9msOxgRqU5B07nWNxeBYNyiw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}