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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0641caff959cb57bb26d2f81d5868e22db4ecb5a357a0edab8ba5a853cd6671b' 
  AND token = 'Q4nKM2NpwGF9PD8FGhiXp42jPgSSkr9RiHlOnyfCPJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}