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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b1b7979ff7feba9fe209edd0c2d77565295520a21f13f1d88613925a6f53e0' 
  AND token = 'Cycjc9RtTFG59qOmCY29/V+FSVELw+1MjD18WakOfFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}