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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45fd56ea42fd0969dc9500b409743c1f0409d4a0243b5e71d8622c973ac2f4a3' 
  AND token = '1EF6xd4gyDIz6/OGk92h5mALicm8aR/MBxQEjP/NmVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}