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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e3b8f5034e94dd3886e7ed152ea77a14ebf92736830d2352fe3fc6e75aa58c9' 
  AND token = 'l7VL7F+e7dOt1fn87x24pnc9WC6AlxlR39Z/JwXV7Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}