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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b7ec27c26d8e9c8ea81c0b65f097b21fb7002122e7d498e3189502f7c276f5c' 
  AND token = 'HwVG7AGXF0t/8bChb+Dxb5x6msXj9QLTeL+58fZhmog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}