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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87b8cfa28b3fce14f9b3dde72c16a61e4e61353a0eaf52f7216a5fa94308f332' 
  AND token = 'qS7nTVV1yJtqLl+o5k6LZWLRxnLLV4Th1kTZMb6FZZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}