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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1040ddb548f18c363f7263c369073bff1a1f78c63252d9db3c7664cb74208273' 
  AND token = 'i1nMNPgKM4sjB9nMhhYzHzY5nnRfVeDTnQkAT8o5WSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}