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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4fc251be9bd4952582a33d56b9a9bc1fbeb32832a1e0240d25caeafaa966b9' 
  AND token = 'zkRoOCl0eku8yyPPOhNO+CU5rQr0//X735hAZoD5xd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}