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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e995c711f069018769a4bf3a7591808eefbdf7d250b862503eee7c15578b859' 
  AND token = 'SPis9yoek++bzSYY5JmfustvlMuwgQoxY4bv7af1mV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}