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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58046b0e02928e2650276a122ca752d9186b166d8ae67d86be8fa535dae2237e' 
  AND token = '+HNLLTgMDRWpoz8uUOZj7BiqrSUW4wreFxYwky6UMjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}