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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1126dce7646b1527cd0729742b857c05cdf091d1d707dd464fc7c44f6a1d4e7' 
  AND token = 'XYHeNMHDN+3KHNYWpsAT2n8erVjHciahbSXMk7mU5VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}