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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '733c255445bd61996f8c1a4b9eda53f5b23ce7ec2e3da000b43a7ad22f4c3d42' 
  AND token = 'tsY1IVbERqKnBuiwlKqRqnMbbDVY6Dg02rASjOaj1lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}